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2023
Systematic Review
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Continuous digital hypothermia for prevention and treatment of equine acute laminitis: A practical review.

Authors: Lavado, Lewis, Montgomery

Journal: Veterinary journal (London, England : 1997)

Summary

# Editorial Summary: Continuous Digital Hypothermia for Acute Equine Laminitis Laminitis remains one of the most challenging conditions in equine practice, and early intervention is critical to preventing irreversible lamellae damage. Lavado, Lewis, and Montgomery conducted a comprehensive review of 19 publications examining continuous digital hypothermia (CDH) as both a preventative and therapeutic tool, evaluating various cooling methods including commercial ice boots, fluid-filled bags, gel packs, and prototype perfused cuffs. The evidence demonstrates that CDH exerts multiple protective mechanisms—notably inflammatory modulation, profound vasoconstriction, and direct tissue preservation—with cooling maintained below 10°C proving most effective, and 12 experimental studies documenting significant improvements in clinical outcomes, immunological markers, and histological integrity of the lamellae. Whilst the clinical benefit of cryotherapy is well-established across different stages of laminitis, current practical limitations—including labour intensity, dependency on reliable ice supplies, and cost—restrict its application in many ambulatory and field settings. The authors emphasise an urgent need for development of more accessible, user-friendly cryotherapy systems that maintain efficacy without compromising practicality, which would substantially expand therapeutic options for practitioners managing horses at risk of or presenting with acute laminitis.

Read the full abstract on PubMed

Practical Takeaways

  • CDH is evidence-supported for both prevention and early treatment of acute laminitis, with low risk of adverse effects, making it a valuable tool for at-risk horses
  • Current ice boot and ice bag methods work but are labor-intensive and impractical in many field settings—continue using them when feasible, but recognize the need for better solutions
  • Maintaining hoof temperature below 10°C is the target; monitor cooling effectiveness regularly as labor demands and ice availability may compromise compliance in long-term applications

Key Findings

  • Continuous digital hypothermia modulates inflammatory response, produces profound vasoconstriction, and prevents tissue damage in lamellae
  • Nineteen publications evaluated CDH methods; twelve experimental studies found multiple positive effects on clinical improvement, immunological modulation, and histological protection
  • Optimal cooling temperature is below 10°C, but current methods face limitations including labor intensiveness, reliance on ice sources, and cost barriers to practical use
  • Despite clinical efficacy evidence, safer, more user-friendly, and effective cryotherapy methods are needed for both hospital and ambulatory settings

Conditions Studied

acute laminitislaminitis prevention